Featured publications
Real-time quaking-induced conversion assays for prions: Applying a sensitive but imperfect test in clinical practice
July 1, 2023
Jones SM, Lazar EB, Porter AL, Prusinski CC, Brier MR, Bucelli RC, Day GS. Real-time quaking-induced conversion assays for prions: Applying a sensitive but imperfect test in clinical practice. Eur J Neurol. 2023 Jul;30(7):1854-1860. doi: 10.1111/ene.15795. Epub 2023 Apr 3. PMID: 36940265; PMCID: PMC10247483.
“Brain age” predicts disability accumulation in multiple sclerosis
June 1, 2023
Brier MR, Li Z, Ly M, Karim HT, Liang L, Du W, McCarthy JE, Cross AH, Benzinger TLS, Naismith RT, Chahin S. “Brain age” predicts disability accumulation in multiple sclerosis. Ann Clin Transl Neurol. 2023 Jun;10(6):990-1001. doi: 10.1002/acn3.51782. Epub 2023 Apr 29. PMID: 37119507; PMCID: PMC10270248.
Quantitative MRI identifies lesional and non-lesional abnormalities in MOGAD
May 1, 2023
Brier MR, Xiang B, Ciotti JR, Chahin S, Wu GF, Naismith RT, Yablonskiy D, Cross AH. Quantitative MRI identifies lesional and non-lesional abnormalities in MOGAD. Mult Scler Relat Disord. 2023 May;73:104659. doi: 10.1016/j.msard.2023.104659. Epub 2023 Mar 23. PMID: 37004272.
Increased white matter glycolysis in humans with cerebral small vessel disease
November 1, 2022
Brier MR, Blazey T, Raichle ME, Morris JC, Benzinger TLS, Vlassenko AG, Snyder AZ, Goyal MS. Increased white matter glycolysis in humans with cerebral small vessel disease. Nat Aging. 2022 Nov;2(11):991-999. doi: 10.1038/s43587-022-00303-y. Epub 2022 Nov 10. PMID: 37118084; PMCID: PMC10155263.
Phase 1 Evaluation of 11C-CS1P1 to Assess Safety and Dosimetry in Human Participants
November 1, 2022
Brier MR, Hamdi M, Rajamanikam J, Zhao H, Mansor S, Jones LA, Rahmani F, Jindal S, Koudelis D, Perlmutter JS, Wong DF, Nickels M, Ippolito JE, Gropler RJ, Schindler TH, Laforest R, Tu Z, Benzinger TLS. Phase 1 Evaluation of 11C-CS1P1 to Assess Safety and Dosimetry in Human Participants. J Nucl Med. 2022 Nov;63(11):1775-1782. doi: 10.2967/jnumed.121.263189. Epub 2022 Mar 24. PMID: 35332093; PMCID: PMC9635683.
- Improving Early Recognition of Treatment-Responsive Causes of Rapidly Progressive Dementia: The STAM3P ScoreSatyadev, N., Tipton, P. W., Martens, Y., Dunham, S. R., Geschwind, M. D., Morris, J. C., Brier, M. R., Graff-Radford, N. R. & Day, G. S., Feb 2024, In: Annals of neurology. 95, 2, p. 237-248 12 p.Research output: Contribution to journal › Article › peer-review
- Diagnostic Utility of Cerebrospinal Fluid Biomarkers in Patients with Rapidly Progressive DementiaKuchenbecker, L. A., Tipton, P. W., Martens, Y., Brier, M. R., Satyadev, N., Dunham, S. R., Lazar, E. B., Dacquel, M. V., Henson, R. L., Bu, G., Geschwind, M. D., Morris, J. C., Schindler, S. E., Herries, E., Graff-Radford, N. R. & Day, G. S., Feb 2024, In: Annals of neurology. 95, 2, p. 299-313 15 p.Research output: Contribution to journal › Article › peer-review
- Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 RadiotracerQiu, L., Jiang, H., Cho, K., Yu, Y., Jones, L. A., Huang, T., Perlmutter, J. S., Gropler, R. J., Brier, M. R., Patti, G. J., Benzinger, T. L. S. & Tu, Z., 2024, (Accepted/In press) In: ACS Chemical Neuroscience.Research output: Contribution to journal › Article › peer-review
- T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer diseaseRahmani, F., Brier, M. R., Gordon, B. A., McKay, N., Flores, S., Keefe, S., Hornbeck, R., Ances, B., Joseph-Mathurin, N., Xiong, C., Wang, G., Raji, C. A., Libre-Guerra, J. J., Perrin, R. J., McDade, E., Daniels, A., Karch, C., Day, G. S., Brickman, A. M., Fulham, M., & 14 othersJack, C. R., la La Fougère, C., Reischl, G., Schofield, P. R., Oh, H., Levin, J., Vöglein, J., Cash, D. M., Yakushev, I., Ikeuchi, T., Klunk, W. E., Morris, J. C., Bateman, R. J. & Benzinger, T. […]
- Quantitative Analysis of S1PR1 Expression in the Postmortem Multiple Sclerosis Central Nervous SystemJiang, H., Zhou, C., Qiu, L., Gropler, R. J., Brier, M. R., Wu, G. F., Cross, A. H., Perlmutter, J. S., Benzinger, T. L. S. & Tu, Z., Nov 15 2023, In: ACS Chemical Neuroscience. 14, 22, p. 4039-4050 12 p.Research output: Contribution to journal › Article › peer-review
- Measuring Pathology in Patients with Multiple Sclerosis Using Positron Emission TomographyBrier, M. R. & Taha, F., Sep 2023, In: Current neurology and neuroscience reports. 23, 9, p. 479-488 10 p.Research output: Contribution to journal › Review article › peer-review
- Real-time quaking-induced conversion assays for prions: Applying a sensitive but imperfect test in clinical practiceJones, S. M., Lazar, E. B., Porter, A. L., Prusinski, C. C., Brier, M. R., Bucelli, R. C. & Day, G. S., Jul 2023, In: European Journal of Neurology. 30, 7, p. 1854-1860 7 p.Research output: Contribution to journal › Article › peer-review
- “Brain age” predicts disability accumulation in multiple sclerosisBrier, M. R., Li, Z., Ly, M., Karim, H. T., Liang, L., Du, W., McCarthy, J. E., Cross, A. H., Benzinger, T. L. S., Naismith, R. T. & Chahin, S., Jun 2023, In: Annals of Clinical and Translational Neurology. 10, 6, p. 990-1001 12 p.Research output: Contribution to journal › Article › peer-review
- Quantitative MRI identifies lesional and non-lesional abnormalities in MOGADBrier, M. R., Xiang, B., Ciotti, J. R., Chahin, S., Wu, G. F., Naismith, R. T., Yablonskiy, D. & Cross, A. H., May 2023, In: Multiple Sclerosis and Related Disorders. 73, 104659.Research output: Contribution to journal › Article › peer-review
- Increased white matter glycolysis in humans with cerebral small vessel diseaseBrier, M. R., Blazey, T., Raichle, M. E., Morris, J., Benzinger, T. L. S., Vlassenko, A. G., Snyder, A. & Goyal, M., Nov 2022, In: Nature Aging. 2, 11, p. 991-999 9 p.Research output: Contribution to journal › Article › peer-review